Wednesday, July 31, 2019

Proposal Eye Clinic System

Table Content 1. Introduction †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 3 2. Planning Phase 1. Problem statement†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ 4 2. Objective†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 4 3. Scopes 1. User Scope†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 5 2. System Scope†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã ¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦. 5 3.Software Requirement†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 6 4. Analysis Phase 1. Methodologies†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦. 6 1. Planning†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ 6 2. Analysis†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ 6 3. Design†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â ‚¬ ¦ 7 4. Implementation†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦. 7 5. Diagram 1. Flow chart†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦ – 15 2. Entity Relationship Diagram (ERD)†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 16 3. Data Flow Diagram (DFD)†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 17 – 19 6. Conclusion †¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦. 20 7. Appendix 1. Interface design†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦.. 21 – 42 INTRODUCTION LaserPro Eye Centre Clinic System is a system where it is an eyes specialist clinic and is a place where the patient gets supervision from doctors about eyes diseases.Laser Pro Eye Centre clinic system is having unstable and lack of capability in managing the clinic. For example, this system cannot store the information of the patients and the diagnosis of the doctors. This is due to they are still using the manual ways in handling their patient records. Therefore, they will need to look for the records and it will be troublesome if the records have been kept for a year. Besides that, there will be a need in calculating the medical fees. It will be not efficient if they are still using the manual way to do the calculation.After that this system also will print the receipt and the report. Therefore, this system is developing to make the management of the clinic more systematically, easier and smooth. This clinic will do some charity, like didn’t count the consultation fee for all the patients, the poor people also afford to pay the medical fee. Because some patient not affordable to pay the expensive medical fees, they will choose don’t want go for treatment, maybe will cause the disease become serious.This system is a system were using the first come first serve method, so it will not provided appointment for the patients to book the appointment, because this is not fair for those walk in patients if they come early in the morning but because of the appointment patients, they have to wait until doctor finished the appointment patients first only diagnose them. In this system, I will include some modules. These modules are login, searching for the staff information, product information, and patient information, calculation for medication fee, delete and update module, clear, print receipt PLANNING PHASE Problem StatementThere is a few problem that occur if there is no systematic system for this clinic. It will be taking longer time to look for the records of the patient and medical dispenses. Besides that, it also require larger storage place, not environment friendly since they are using papers in keeping the records and the inactive records which have been put aside must have been lost. Besides that, some of the records are missing due to the large amout of patients record or information. In addition, manual method which required many processes such as finding old details that have been kept for a year is quite troublesome.OBJECTIVE The main purpose is to automate LaserPro Eye Centre clinic management system. The derivative are as follows: †¢ To automate the staff information system. †¢ To automate the product information system. †¢ To automate the patient information system. †¢ To automate sales report and product list. †¢ To automate the calculation of the medical fee. SCOPE User Scope: The target user s of this system are the doctors and nurses of LaserPro Eye Centre Clinic System. With this system,admin are able to : 1. Login into the system using security password. . View, update, add, and search details of staff information. 3. View, update, add, delete, and search details of product information. 4. View, update, add, delete, and search the patient information. 5. View sales report, and stock report according to overall sales, by day. Print out the report. 6. Calculate for the medication fees and print the receipt. With this system, staffs are able to: 1. Login into the system using security password. 2. View, update, add, and search details of staff information, but can’t update particular details. 3.View, update, add, delete, and search details of product information. 4. View, update, add, delete, and search the patient information, but can’t add or update the treatment of the patient. 5. View sales report, and stock report according to overall sales, by day. P rint out the report. 6. Calculate for the medication fees and print the receipt. System scope: The system use in LaserPro Eye Centre and its major function are: 1. Security password is required to allow admin and staffs to login into the system. 2. Store records of staff in database. 3. Store details of product in database. . Store details of patient in database. 5. Can calculate the medication fees and print the receipts for the patient. 6. Searching function which enables the admin and staff to look for patient records. 7. Help function to guide user in using this system. Software Requirement: 1. Microsoft Visual Basic. Net 2008: use to create or build interface of †LaserPro Eye Centre Clinic System†. 2. Microsoft Office Access 2007. 3. Microsoft Office Visio 2007. ANALYSIS PHASE Methodologies The methodology that was used to create the LaserPro Eye Centre is the System Development Life Cycle (SDLC).It comprises of 4 stages which are planning, analysis, design and impl ementation. PLANNING †¢ The system is built for easily search and find needed information of the clinic for the Admin and the staff of the clinic. †¢ The users would want search and find the staff information, patient information, product information in a quick and effective way. And also calculate the medical fee for the patient. †¢ The system is to be built by using the Visual Basic. Net programming language from the Visual Studio. Net software. ANALYSIS The users of the system are people who want to search, add, update, clear and delete the staff information, product information, patient information. †¢ The LaserPro Eye Centre will display the staff information, product information, patient information, calculation for medical fee, and the sales report that the users searched. †¢ Besides, there is a print button to let the user print out the receipt of the medical fee, sales report, product information the users has counted and searched. †¢ The syste m can only be used in LaserPro Eye Centre Clinic. DESIGN In the manager menu and the main menu, the users can select the staff, product, and patient information that they want to search or update. †¢ When the users choose to search the information, the information will be display. †¢ The users can calculate the medical fee using the calculation page. After calculated the medical fee, also can print out the sales report and the stock report. †¢ When the users choose to update the information, the users are allow to add, update, edit and delete the information. †¢ They can exit the system any time they feel like doing so.IMPLEMENTATION †¢ The system is supposed to be delivered by the 14th week and presented on the 15th week. †¢ The system is test before deliver. Flow Chart Login [pic] Forget Password [pic] Manager MenuMain Menu [pic] Staff Information [pic] Product Information [pic] Patient information [pic] Sale Information [pic] Sale Calculation [pic] E ntity Relationship Diagram (ERD) [pic] Data Flow Diagram (DFD) Context Diagram [pic] †¢ Level 1, Process 1 and Process 2 : [pic] †¢ Level 2, Process 1, and Process 2 [pic] †¢ Level 1, Process 3 and Process 4 : [pic] CONCLUSION:After going through all the processes and procedures involved, I have succeeded build the LaserPro Eye Centre Clinic System. With this system, users will no longer have difficulty in searching, editing, adding, calculating and deleting the details that they wanted. Besides that, they can save their time and easy in doing so. This system is created for two users to use which are admin and staff. Other than that, these systems have some feature that can be use and seen by staff so these systems can be avoiding the staff to see other user feature. Besides that, if user have forgotten their password. They can

Tuesday, July 30, 2019

Glutathione

Glutathione (GSH) is a tripeptide that contains an unusual peptide linkage between the amine group of cysteine (which is attached by normal peptide linkage to a glycine) and the carboxyl group of the glutamate side-chain. It is an antioxidant, preventing damage to important cellular components caused by reactive oxygen species such as free radicals and peroxides. [2] Thiol groups are reducing agents, existing at a concentration of approximately 5 mM in animal cells. Glutathione reduces disulfide bonds formed within cytoplasmic proteins to cysteines by serving as an electron donor. In the process, glutathione is converted to its oxidized form glutathione disulfide (GSSG), also called L(-)-Glutathione. Glutathione is found almost exclusively in its reduced form, since the enzyme that reverts it from its oxidized form, glutathione reductase, is constitutively active and inducible upon oxidative stress. In fact, the ratio of reduced glutathione to oxidized glutathione within cells is often used as a measure of cellular toxicity. 3] Glutathione is not an essential nutrient (meaning it does not have to be obtained via food), since it can be synthesized in the body from the amino acids L-cysteine, L-glutamic acid, and glycine. The sulfhydryl (thiol) group (SH) of cysteine serves as a proton donor and is responsible for the biological activity of glutathione. Provision of this amino acid is the rate-limiting factor in glutathione synthesis by the cells, since cysteine is relatively rare in foodstuffs. Furthermore, if released as the free amino acid, cysteine is toxic and spontaneously catabolized in the gastrointestinal tract and blood plasma. [4] Glutathione is synthesized in two adenosine triphosphate-dependent steps: * First, gamma-glutamylcysteine is synthesized from L-glutamate and cysteine via the enzyme gamma-glutamylcysteine synthetase (a. k. a. glutamate cysteine ligase, GCL). This reaction is the rate-limiting step in glutathione synthesis. citation needed] * Second, glycine is added to the C-terminal of gamma-glutamylcysteine via the enzyme glutathione synthetase. Animal glutamate cysteine ligase (GCL) is a heterodimeric enzyme composed of a catalytic (GCLC) and modulatory (GCLM) subunit. GCLC constitutes all the enzymatic activity, whereas GCLM increases the catalytic efficiency of GCLC. Mice lacking GCLC (i. e. , all de novo GSH synthesis) die before birth. [5] Mice lacking GCLM demonstrate no outward phenotype, but exhibit marked decrease in GSH and increased sensiti vity to toxic insults. 6][7][8] While all cells in the human body are capable of synthesizing glutathione, liver glutathione synthesis has been shown to be essential. Mice with genetically-induced loss of GCLC (i. e. , GSH synthesis) only in the liver die within 1 month of birth. [9] The plant glutamate cysteine ligase (GCL) is a redox-sensitive homodimeric enzyme, conserved in the plant kingdom. [10] In an oxidizing environment, intermolecular disulfide bridges are formed and the enzyme switches to the dimeric active state. The mid-point potential of the critical cysteine pair is -318 mV. In addition to the redox-dependent control is the plant GCL enzyme feedback inhibited by GSH. [11] GCL is exclusively located in plastids, and glutathione synthetase is dual-targeted to plastids and cytosol, thus are GSH and gamma-glutamylcysteine exported from the plastids. [12] Both glutathione biosynthesis enzymes are essential in plants; knock-outs of GCL and GS are lethal to embryo and seedling. [13] The biosynthesis pathway for glutathione is found in some bacteria, like cyanobacteria and proteobacteria, but is missing in many other bacteria. Most eukaryotes synthesize glutathione, including humans, but some do not, such as Leguminosae, Entamoeba, and Giardia. The only archaea that make glutathione are halobacteria. [14][15] [edit] Function Glutathione exists in reduced (GSH) and oxidized (GSSG) states. In the reduced state, the thiol group of cysteine is able to donate a reducing equivalent (H++ e-) to other unstable molecules, such as reactive oxygen species. In donating an electron, glutathione itself becomes reactive, but readily reacts with another reactive glutathione to form glutathione isulfide (GSSG). Such a reaction is possible due to the relatively high concentration of glutathione in cells (up to 5 mM in the liver). GSH can be regenerated from GSSG by the enzyme glutathione reductase. In healthy cells and tissue, more than 90% of the total glutathione pool is in the reduced form (GSH) and less than 10% exists in the disulfide form (GSSG). An increased GSSG-to-GSH ratio is considered indicative of oxidative str ess. Glutathione has multiple functions: It is the major endogenous antioxidant produced by the cells, participating directly in the neutralization of free radicals and reactive oxygen compounds, as well as maintaining exogenous antioxidants such as vitamins C and E in their reduced (active) forms. [16][citation needed] * Regulation of the nitric oxide cycle, which is critical for life but can be problematic if unregulated [17] * Through direct conjugation, it detoxifies many xenobiotics (foreign compounds) and carcinogens, both organic and inorganic. This includes heavy metals such as mercury, lead, and arsenic. [citation needed] * It is essential for the immune system to exert its full potential, e. g. , (1) modulating antigen presentation to lymphocytes, thereby influencing cytokine production and type of response (cellular or humoral) that develops, (2) enhancing proliferation of lymphocytes, thereby increasing magnitude of response, (3) enhancing killing activity of cytotoxic T cells and NK cells, and (4) regulating apoptosis, thereby maintaining control of the immune response. citation needed] * It plays a fundamental role in numerous metabolic and biochemical reactions such as DNA synthesis and repair, protein synthesis, prostaglandin synthesis, amino acid transport, and enzyme activation. Thus, every system in the body can be affected by the state of the glutathione system, especially the immune system, the nervous system, the gastrointestinal system and the lungs. [4] Function in animals GSH is known as a substrate in both conjugation reactions and reduction reactions, catalyzed by glutathione S-transferase enzymes in cytosol, microsomes, and mitochondria. However, it is also capable of participating in non-enzymatic conjugation with some chemicals. In the case of N-acetyl-p-benzoquinone imine (NAPQI), the reactive cytochrome P450-reactive metabolite formed by paracetamol (or acetaminophen as it is known in the US), that becomes toxic when GSH is depleted by an overdose of acetaminophen, Glutathione is an essential antidote to overdose. Glutathione conjugates to NAPQI and helps to detoxify it. In this capacity, it protects cellular protein thiol groups, which would otherwise become covalently modified; when all GSH has been spent, NAPQI begins to react with the cellular proteins, killing the cells in the process. The preferred treatment for an overdose of this painkiller is the administration (usually in atomized form) of N-acetyl-L-cysteine (often as a trademarked preparation called Mucomyst ® [1]), which is processed by cells to L-cysteine and used in the de novo synthesis of GSH. Glutathione (GSH) participates in leukotriene synthesis and is a cofactor for the enzyme glutathione peroxidase. It is also important as a hydrophilic molecule that is added to lipophilic toxins and waste in the liver during biotransformation before they can become part of the bile. Glutathione is also needed for the detoxification of methylglyoxal, a toxin produced as a by-product of metabolism. This detoxification reaction is carried out by the glyoxalase system. Glyoxalase I (EC 4. 4. 1. ) catalyzes the conversion of methylglyoxal and reduced glutathione to S-D-lactoyl-glutathione. Glyoxalase II (EC 3. 1. 2. 6) catalyzes the hydrolysis of S-D-lactoyl-glutathione to glutathione and D-lactic acid. Glutathione has recently been used as an inhibitor of melanin in the cosmetics industry. In countries like Japan and the Philippines, this product is sold as a whitening soap. Glutathione competitively inhibits melanin synthesis in the reaction of tyrosinase and L-DOPA by interrupting L-DO PA's ability to bind to tyrosinase during melanin synthesis. The inhibition of melanin synthesis was reversed by increasing the concentration of L-DOPA, but not by increasing tyrosinase. Although the synthesized melanin was aggregated within 1 h, the aggregation was inhibited by the addition of glutathione. These results indicate that glutathione inhibits the synthesis and agglutination of melanin by interrupting the function of L-DOPA. â€Å"[18] Function in plants In plants, glutathione is crucial for biotic and abiotic stress management. It is a pivotal component of the glutathione-ascorbate cycle, a system that reduces poisonous hydrogen peroxide. 19] It is the precursor of phytochelatins, glutathione oligomeres that chelate heavy metals such as cadmium. [20] Glutathione is required for efficient defence against plant pathogens such as Pseudomonas syringae and Phytophthora brassicae. [21] APS reductase, an enzyme of the sulfur assimilation pathway uses glutathione as electron donor. Other enzymes using glutathione as substrate are glutare doxin, these small oxidoreductases are involved in flower development, salicylic acid and plant defence signalling. [22] [edit] Supplementation Raising GSH levels through direct supplementation of glutathione is difficult. Research suggests that glutathione taken orally is not well absorbed across the gastrointestinal tract. In a study of acute oral administration of a very large dose (3 grams) of oral glutathione, Witschi and coworkers found â€Å"it is not possible to increase circulating glutathione to a clinically beneficial extent by the oral administration of a single dose of 3 g of glutathione. â€Å"[23][24] Vitamin D increases glutathione levels in the brain and appears to be a catalyst for glutathione production. 25] The amount of activated vitamin D in the brain is tied to how much vitamin D3 one has, either ingested through supplements or created in the skin via sun exposure. This suggests taking vitamin D3 supplements and/or getting adequate sun exposure boosts glutathione production. In addition, plasma and liver GSH concentrations can be raised by administration of certain supplements that serve as GSH precu rsors. N-acetylcysteine, commonly referred to as NAC, is the most bioavailable precursor of glutathione. 26] Other supplements, including S-adenosylmethionine (SAMe)[27][28][29] and whey protein[30][31][32][33][34][35] have also been shown to increase glutathione content within the cell. NAC is available both as a drug and as a generic supplement. Alpha lipoic acid has also been shown to restore intracellular glutathione. [36][37] Melatonin has been shown to stimulate a related enzyme, glutathione peroxidase,[38] and silymarin, an extract of the seeds of the milk thistle plant (Silybum marianum) has also demonstrated an ability to replenish glutathione levels. [39][40] Glutathione is a tightly regulated intracellular constituent, and is limited in its production by negative feedback inhibition of its own synthesis through the enzyme gamma-glutamylcysteine synthetase, thus greatly minimizing any possibility of over dosage. Glutathione augmentation using precursors of glutathione synthesis or intravenous glutathione is a strategy developed to address states of glutathione deficiency, high oxidative stress, immune deficiency, and xenobiotic overload in which glutathione plays a part in the detoxification of the xenobiotic in question (especially through the hepatic route). Glutathione deficiency states include, but are not limited to, HIV/AIDS, chemical and infectious hepatitis, myalgic encephalomyelitis chronic fatigue syndrome ME / CFS,[41][42][43] prostate and other cancers, cataracts, Alzheimer's disease, Parkinson's disease, chronic obstructive pulmonary disease, asthma, radiation poisoning, malnutritive states, arduous physical stress, and aging, and has been associated with suboptimal immune response. Many clinical pathologies are associated with oxidative stress and are elaborated upon in numerous medical references. [4][44][45] Low glutathione is also strongly implicated in wasting and negative nitrogen balance,[46] as seen in cancer, AIDS, sepsis, trauma, burns and even athletic overtraining. Glutathione supplementation can oppose this process, and in AIDS, for example, result in improved survival rates. [47] However, studies in many of these conditions have not been able to differentiate between low glutathione as a result of acutely (as in septic patients) or chronically (as in HIV) increased oxidative stress, and increased pathology as a result of preexisting deficiencies. Schizophrenia and bipolar disorder are associated with lowered glutathione. Accruing data suggest that oxidative stress may be a factor underlying the pathophysiology of bipolar disorder (BD), major depressive disorder (MDD), and schizophrenia (SCZ). Glutathione (GSH) is the major free radical scavenger in the brain. [48] Diminished GSH levels elevate cellular vulnerability towards oxidative stress; characterized by accumulating reactive oxygen species. Replenishment of glutathione using N-acetyl cysteine has been shown to reduce symptoms of both disorders. citation needed] Cancer Preliminary results indicate glutathione changes the level of reactive oxygen species in isolated cells grown in a laboratory,[49][50] which may reduce cancer development. [51] [52] None of these tests were performed in humans. However, once a cancer has already developed, by conferring resistance to a number of chemotherapeutic drugs, elevated levels of glutathione in tumor cells are able to protect cancer ous cells in bone marrow, breast, colon, larynx, and lung cancers. 53] [edit] Pathology Excess glutamate at synapses, which may be released in conditions such as traumatic brain injury, can prevent the uptake of cysteine, a necessary building-block of glutathione. Without the protection from oxidative injury afforded by glutathione, cells may be damaged or killed. [54] Methods to determine glutathione Reduced glutathione may be visualized using Ellman's reagent or bimane derivates such as monobromobimane. The monobromobimane method is more sensitive. In this procedure, cells are lysed and thiols extracted using a HCl buffer. The thiols are then reduced with dithiothreitol (DTT) and labelled by monobromobimane. Monobromobimane becomes fluorescent after binding to GSH. The thiols are then separated by HPLC and the fluorescence quantified with a fluorescence detector. Bimane may also be used to quantify glutathione in vivo. The quantification is done by confocal laser scanning microscopy after application of the dye to living cells. 55] Another approach, which allows to measure the glutathione redox potential at a high spatial and temporal resolution in living cells is based on redox imaging using the redox-sensitive green fluorescent protein (roGFP)[56] or redox sensitive yellow fluorescent protein. . When we speak of glutathione, what will really come to mind is that glutathione which most Filipino thought of as a whitening agent. It comes in soaps and any other beauty products which hopefully will make one whiter and fairer when used. But what we really don’t know is that glutathione is found in each of three trillion cells in our body. It is the most powerful an antioxidant which we cannot find in a fruit or in a berry a common but it is found in our body. In fact its absence will make one die. In my first blog I ‘ve told you about the glutathione story. Now I’m going to tell you what glutathione really is and its role to our over all well being. So what is glutathione really: Glutathione is a tripeptide, What is glutathione?

Monday, July 29, 2019

Book Review Bachelor Essay Example | Topics and Well Written Essays - 1250 words

Book Review Bachelor - Essay Example Thus, Crossing the Border is generally acknowledged by scholars as a fundamental book that chronicles the history of Buxton, one of the most successful all-black settlements in nineteenth-century Canada. In her work, Sharon A. Roger Hepburn traces the evolution of educational institutions, businesses, and political structures in Buxton in the mid-1800s and the focus of the author is on the degree to which black settlers achieved autonomy and the control over their lives in a hostile white environment. The author undertakes an important study of Buxton, Ontario, through a comprehensive study of the manuscripts, newspapers, census records, deeds, maps, and other materials and she is effective in recreating a detailed story of the Black Canadian community through the lives of individual people. According to the author, the Black Canadian community, roughly twelve miles south Chatham, close to the shores of Lake Erie in Raleigh Township, Kent Country, espoused freedom and hope for the fu ture and accepted blacks who were single, married, and widowed; young and old; male and female; freeborn and fugitive. "This study chronicles Buxton from its conception and founding through its first decade. A group of individuals, united in their determination to build a heaven for those fleeing slavery and repressive legal statutes, formed themselves into a community that offered social and economic opportunity. Overcoming initial opposition from neighboring whites and backed by the Presbyterian Church of Canada and philanthropic Canadians of both races, Buxton grew steadily in population and stature." (Hepburn, 1) Therefore, Hepburn provides a convincing account of the Black Canadian community settlement in Buxton, Ontario, and she is effective in explaining why Buxton succeeded when other settlements failed. A careful reading of Crossing the border: A free Black community in Canada by Sharon A. Roger Hepburn confirms that the author eloquently traces the development of Buxton from its conception and founding, and her main focus is to give an explanation for its status as the 'most successful all-black community established in Canada before the U.S. Civil War.' In her attempt to establish the point that the Black Canadian community was the most successful all-black community established in Canada, the author compares this community with similar communities in Canad

Sunday, July 28, 2019

Posters Essay Example | Topics and Well Written Essays - 1500 words

Posters - Essay Example Posters are used in almost all types of industries. Companies use them for advertising their products. They consider posters as one of the important way to reach the customers. It is an effective method of advertising, as most of the people who pass by that poster will definitely take a look at it. Posters can be in the form of banner and hoardings. They are put up at important places so that more number of people will observe it. The advertisers adopt various strategies to attract people. They make sure it reaches people of all strata of the society. They should be easier for the people to understand. The information should be in a short and clear manner. It should be concise and correct. As posters draw the attention of large number of people, the advertisers must be careful in selecting the picture and information. They must ensure that it does not convey any wrong data. Posters communicate with people in a better way than any other medium of advertisement. They are not only used for advertisement. In some cases, posters are used for spreading awareness among the public. Poster reaches the public easily and it is one of the best ways to convey information to the people. They are most sought after by the politicians. As they use it for canvassing during the elections, it acts as the best medium. Posters are a boon to film industry. They make use of posters to advertise about the upcoming movies. They put up the pictures of the film stars so that people will be more interested. It helps them in increasing the number of viewers for their film and it includes the necessary information regarding that film. Some posters include obscene pictures to lure the customers. There should be a censorship to control and have a check on this kind of unhealthy publicity by unwanted elements. This will spoil the future society as a whole and also the culture of our country. A poster depicting the Kumbh mela which is a religious function held in the year 2001. This gathering is conducted every 12years. This poster conveys the Indian tradition and integration as people from various parts of the country assemble to take part in this religious activity. Next poster exhibits the Elephant festival. This takes place every year in Kerala during the month of April and May. This shows the tradition of Kerala, where they consider elephant as an incarnation of god. A poster showing the dance form Bharatanatyam. It is the traditional dance form of Tamilnadu and one of the ancient dance forms in India. This type of poster will be displayed in places where such dance programs are held. This poster depicts the Durga Pooja which is held in West Bengal. It is a religious activity that is being performed every year during the month of October. This exhibits the diversity in the culture within India. This poster shows the boat race that took place in Kerala in the year 2002. It is an example of integration among the people of kerala. This is held every year during the festival of onam. The culture is being followed for many decades. As this race is held in a very grand manner, these kind of posters are put up all over Kerala. This poster of traditional bulfight was put up in villages of Tamilnadu during the pongal festival. Generally known as "jallikattu",this form of bulfight is conducted in Tamilnadu and few other parts of Andhra Pradesh. In this, a bag of money

Saturday, July 27, 2019

Green transportation Research Paper Example | Topics and Well Written Essays - 1000 words

Green transportation - Research Paper Example Any means of transport that has low impacts on the environment including non-motorized transport are regarded as green transport. The energy produced from the sources of energy that are environmentally friendlier relative to the fossil fuel is defined as green energy. All renewable sources of energy are therefore included in green energy and according to the definition nuclear energy can also be included under green energy. Research is in progress around the world to explore new paths that will bring out solutions to the environmental hazards that human beings have to face in the present world. All scientists are of the opinion that increased use of renewable sources of energy can be one potent solution to this problem. Sustainable development and renewable energy uses share an intimate connection. The research acts as the evidence on the importance of keeping the environment pollution free and how using green transportation can emerge as the contributing factor. The results from the research will aware people more on using environment friendly modes of transportation that are fuel efficient and cheap. Apart from the environment point of view the project has an economic viewpoint as well. The less developed countries which lack oil reserves, a significant part of the budget have to be kept to buy oil. Foreign currency moves out of the country and those countries fail to break the vicious circle of ineq uality. An average automobile in United States achieves a fuel economy of 11.6Km/kg. The economy is equivalent to the rate of energy consumption. The figure is 2.5MJ/km for OECD countries. The extraction, transportation as well as refining of automotive fuel necessitate almost 20 percent of crude oil energy (Ulrich, 2006, 8). The usage of energy causes pollution to the environment. Now t is assumed that an individual owns a bicycle and uses it while travelling. Such activities cause zero

Friday, July 26, 2019

Research and develop knowledge on the Atrio PMS system and apply it to Paper

And develop knowledge on the Atrio PMS system and apply it to the Diva hotel( San Francisco) - Research Paper Example When people arrive at the hotel, they have to stroll past an amazing sidewalk of fame, which is the superb Diva sidewalk that has signatures of celebrity guests and entrance directly in its lobby. Recently, the hotel renovated its structure and now it offers most extraordinary features to its customers (Hotel Diva, 2012). Each room in the hotel has been renovated with the most superb amenities that comprise carpeting with cobalt, headboard sculptured with stainless steel, CD players set inside the room, two telephones that have touch-tone and allow global internet data ports, voicemail and fax machine, latest televisions with VCRs, pay-per-view movies, Nintendo, honor bar showcase that has special items of San Francisco, maid services, and fresh newspapers (Stowe, 2012). All dining facilities are superb: California Pizza Kitchen, which offers inside dining and room service, and Starbucks, which is adjacent to the lobby. Along with dining facility, there are top quality day laundry an d dry cleaning services, parking by valets that offer parking within and outside privileges, workout room with complimentary cardio services, video library that has a range of newly released films, a caretaker lounge that has magazines, brochures of tourism in San Francisco, literature on San Francisco, as well as green apples of Granny Smith and a gourmet coffee. The hotel is fully-equipped for business; it offers wireless high-speed internet access (â€Å"The Future of Hospitality is Here†, 2012). The target market of Hotel Diva comprises rich people looking for best quality services and complete access to all mandatory amenities. According to Creamer (2012), Diva Hotel has a reputation for offering customized services that are in accordance with customer demands; its management supports innovation and even has boutique properties that are providing access to ample services in a nearby location. The main objective of Hotel Diva is to exceed customer expectations by providin g superb quality services and instant access to the most diverse range of facilities (Hotel Diva, 2012). ATRIO Property Management System (PMS) PAR Springer-Miller Systems, Inc., commonly known as PSMS is the wholly owned subsidiary of PAR Technology Corporation, which is recognized globally for providing hospitality management systems that are guest-centric, so that hotels, restaurants and all companies of hospitality industry can effectively manage their operations (ParTech, Inc., 2011). The company is well-known for development of ATRIO system for hospitality industry that can revolutionize the operations of all companies present in this particular industry. ATRIO platform of solutions is believed to be the latest generation of hospitality management software, which have been purchased by and built for hotels so that they can maintain their IT infrastructure (â€Å"ATRIO Guest Experience Management†, 2012). Since technological advancements happen on an ongoing basis, it is crucial for companies to upgrade their IT systems so that they have well-designed IT infrastructures that will allow them to integrate all requirements of hotel businesses; ATRIO is the best alternative for IT solutions, as it allows hotel owners to save money and control their IT cost. Every hotel and resort has a choice of deployment either on premises or on cloud or even a combination of

Reflective account for postgraduate activities Essay

Reflective account for postgraduate activities - Essay Example All the same, I believed that my paper was in its comprehensive form. I was only to make a few changes with my lecturers in order to make the presentation easier. I finally made my oral presentation before other intellectuals and stakeholders. The initial part of the conference solely entailed presenting my ideas in concise forms. In the beginning, I made a justification for my study by stating that risk management is an unexplored element in the study of finance. This is because of the empiricism and analysis that studies on risk demands. In the oral presentation, I made my references from a PowerPoint slides that I had prepared on my laptop. This enabled me go through the presentation procedurally as I moved from the most basic parts to the most abstract segments. Thereafter, I faced questions from the audience, which occurred at the end of the presentation. When I began my PhD, I held the idea of testing my thoughts against fellow scholars. This is an ultimate feat for every scholar as other people discuss your findings over an issue. In turn, this is a method of gaining legitimacy in the academia. Gaining legitimacy finally certifies one’s academic products and makes a person gain acceptance among knowledgeable people. This is unlike the undergraduate level where there are no stringent standards over presenting ideas. In this sense, I wanted the foundation for advancing knowledge in the future and produce ideas that gain acceptance across disciplines. I realized that it takes more than a good idea to earn legitimacy in life. During the presentation, I had to develop charm while passing on my ideas. This because charm makes people glued to one’s ideas in spite of abstractions. Besides, I had to learn how to sustain an audience through long sessions. This was also essential for hearing my own inner voice as I made presentations.

Thursday, July 25, 2019

Business environment challenges or trends that threaten the long run Essay

Business environment challenges or trends that threaten the long run performance and survival of the company. Develop a coheren - Essay Example The businesses are also tasked with corporate social responsibility issues and the same time expected to observe business ethics in their daily operations. Facebook Company Case Analysis This company is situated in the United States and it serves over a billion clients in the internet, making it the largest social networking site. Its an internet corporation company that runs the social networking site whereby people express their views and communicate all over the work. By the year 2012, the company had over 4500 employees working on various capacities in the company. The main competitors of Facebook are MySpace, Twitter, LinkedIn, IGLOO, among other companies that offer internet social services (Strategic Management Insight, 2013). STEEPLE Analysis of Facebook SOCIAL TECHNOLOGICAL ECONOMICAL ENVIRONMENTAL POLITICAL LEGAL ETHICAL Lifestyle changes New inventions and development Economic growth Sustainable energy Trade polices Employment laws Reputation Career and leisure attitudes I ndustrial focus on technological effort Taxation Global warming International trade regulations Contract laws Business ethics Labour and social mobility Rate of technological transfer Competition Threats from natural causes Political stability Consumer protection Client confidentiality From the STEEPLE Analysis, the challenges facing Facebook range from social, technological, economical, environmental, political, legal, and ethical problems. The users and the governments have been expressing privacy concerns leading to legal suit against the company (Marketing Mix, 2013). The privacy issues have made most consumers to question the business ethics of the company resulting to reduced confidentiality. Facebook being the market leader in social networking services enjoys the benefits that come with economics of scale, but the company profits are also subjected to global economic performance. The lifestyle changes and social mobility of most users is also affecting the company since some begin to see Facebook as a social interaction site for the younger generation. Facebook pays tax from their businesses with rates changing from time to time thus largely consuming their profits. There is stiff competition from related companies like Twitter and MySpace who have launched aggressive campaigns and products to outshine Facebook. Facebook was a result of technological invention and others are also exploiting the same to come up with other related services that are likely to give Facebook a strong competition. Facebook being a company with global footing is vulnerable to problems with corporate social responsibility being a major concern facing most companies and Facebook is not exempted. All businesses are expected to practice business ethics in their daily operations to avoid conflicts and hence Facebook must abide by it. Competition is a major threat to all businesses as Facebook is facing competition from MySpace, Twitter, and LinkedIn. Challenges facing Facebook Cor porate Social Responsibility (CSR) The role of the business is critical in ensuring that the corporate social responsibility is well taken care of since businesses can only flourish when the communities around them and their ecosystems are well taken care of (Hart, 1995). There is growing recognition that everything we do has a positive or negative impact on

Wednesday, July 24, 2019

Ancient Greece Architecture Research Paper Example | Topics and Well Written Essays - 1000 words

Ancient Greece Architecture - Research Paper Example The most distinctive characteristic of ancient Greek architecture is its temples. Ancient Greek architecture is best recognized for its temples. Many of them are situated all the way through the area, generally as ruins or remains but a lot are still to a large extent intact. The succeeding most significant form of structure that endured all throughout the Hellenic world is the uncovered, open-air theatre. The earliest among them dates all the way back roughly around 350 BC. Each Greek township had these kinds of theatre, which were used for communal and social gatherings and meetings as well as for theatrical presentations and shows. The theatre was typically placed in a hillside right out of the town, and had rows of seats placed one above the other, in a half circle surrounding and around the middle area for the performance or presentation, the orchestra. Behind that was a building called the skene. This functioned as a dressing room for the performers, a storage room for props, e tc. and as background scenery to the action happening in the orchestra. A couple of Greek open-air theatres have survived and remained nearly undamaged. The best known among all is located at Epidaurus. The architect who designed this theatre was Polykleitos the Younger who was also a sculptor of athletes and the architect of Tholos. Aside from the theatre, there are also other architectural structures that are even now still in sight. One of them is the processional entry used for ceremonies. This gateway is called the propylon. A storied row of pillars called the stoa borders the agora, or the public square. The town building where the ruling body meets called the bouleuterion can also still be seen in some places. Others include the public memorial, the massive mausoleums and the stadium as well. Towns in Greece with a population of significant size also had a gymnasium or palaestra. This was the public center for males. This included watcher/spectator sections, baths, lavatories , and clubrooms as well. There were other sport-associated buildings. One of the most significant in ancient Greece was the hippodrome, used for horseracing. Only bits and pieces of the hippodromes have lasted. The stadium used for for foot races were 600 feet in length. A number of them exist in different places, which includes the ones in Olympia, Epidarus, Delphi and Ephesus. The 45,000-seating Panathinaiko Stadium which is situated in the Greek city of Athens, was repaired and restored back in the 1800s. It was later used in a number of Olympic Games, the ones held in 1896, 1906 and 2004 Olympic Games. Ancient Greek architecture is known for its greatly formal distinctiveness, equally of formation and ornamentation. Temples were frequently lifted up on elevated ground so that the sophistication of its magnitude and the effect of daylight on its exterior features might be observed from all perspectives. Nikolaus Pevsner refers to these magnificent architectural structures,  "placed before us with a physical presence more intense, more alive than that of any later building". The official terms of Ancient Greek architecture, in particular the dissection of architectural manner. Stylistically, the architecture of Ancient Greece is separated into three â€Å"orders†: the Doric Order, the Ionic Order and the Corinthian Order. The names of these orders reveal their origin. The Doric Order, th

Tuesday, July 23, 2019

Personal & Career Development Programme Essay Example | Topics and Well Written Essays - 750 words

Personal & Career Development Programme - Essay Example You will carry out a literature search on a business in a specific sector which forms a short report in the journal. The focus of the research should be on their business model, products or services, potential business developments, customer or client base. This is designed to help you prepare for questions in an interview which ask you to display knowledge of their business operations. In carrying out the research you should avoid relying solely on information published by the organization and look for independent views and analysis. Google Business Model Google has made enviable strides in a very short time. The company is only in its thirteenth year but it is bigger than many older companies (Google, 2011). The main mode of income generating at goggle is advertising (Betz, 2011). They place advertisements on various products, which they provide free (Murthy, 2007). They even allow users to share in the advertising fees through Google Adwords and Google Adsense (Hill, 2004). In sho rt, Google provides multiple platforms for advertisers to put their advertisements and provides services to end users without cost. Products and Services Google has a very wide range of products. The most popular ones are the Google search engine and Gmail (Hochman, 2010). The search engine helps internet users to find information from the internet based on keywords (Girard, 2009). Gmail on the other hand is a free email platform that allows users to send and receive emails among other services. Other service offered by Google is the YouTube service. This was an acquisition by Google to help in prop its web presence. In addition, there are services such as Blogger through which Google to give free blogs. Potential Business Developments Google has been in the process of improving its services (Gaist, 2009). One of the recent, changes are the upgrade of the appearance of its search engine and the impending system wide change of the appearance of the Gmail email platform. As a company, Google generally avoids making too many changes on its products, opting to build on existing ones by adding optional functionalities to them (Rothkopf, 2009). A case in point is the recent introduction of Google+, which is Google’s attempt at entering the social media scene. It is simply an extension of Gmail. This ideal also shows in Google’s concept of a single sign in. Once a user signs in to any of Google’s applications, they can access all other products provided they registered to use it. Another interesting development that Google is pushing through is Google Places. This application will make it possible for people to know in real time where others are, based on their cell phone signal (Bailyn & Bailyn, 2011). This product is yet to hit the market in a big way, but it will become significant when people get comfortable with others knowing where they are at any one time. Customer Base Google’s customers are the advertisers who put up their adverts on the platforms Google provides (Betz, 2011). End users of the services are not the customers of the company (Paliwal, 2006). They do not generate revenue for Google. They simply provide Google with potential consumer groups to whom the company’s customers can advertise. Reference List Bailyn, E. & Bailyn, B., 2011. Outsmarting Google: SEO Secrets to Winning New Business. Que Publishing. Betz, F., 2011.

Monday, July 22, 2019

The New NYSE Essay Example for Free

The New NYSE Essay The year 2006 witnessed dynamic changes in the structure of the New York Stock Exchange. For the first time in 214 years, the not-for-profit NYSE transformed itself into a for-profit, public company. This occurred following NYSE Group Inc.’s acquisition of the electronic rival, Archipelago Holdings Incl. in early 2006. It feels good, remarked John Thain, chief executive of NYSE Group and the creator of the deal to change NYSE’s status. He added: Now, of course, we have to demonstrate to our shareholders that theres real value to be had here. (Martinez, 2006) Unsurprisingly, investors expressed utter delight in the knowledge that they now would be given the chance to make great profits through NYSE. In fact, the welcome received by the new status of NYSE as a public company, saw shares of the newly public stock exchange up thirteen percent in its first trading session alone. The company began trading under the ticker symbol, NYX. Both Thain and NYSE Group Chairman Marshall Carter happened to be the first to purchase 100 shares each at $67 in ceremonial first trades. The price of shares was up $2.75 from Archipelago’s close before the status of NYSE was changed. After this, the stock continued to climb, and by midday was up $8.11. Moreover, the volume of trading at the for-profit NYSE was ten times that of Archipelago’s average daily trade (Martinez). The benefits of NYSE’s change of status are overwhelming as well as self-evident. In the fourth quarter of 2005, the largest United States equities exchange had run into a loss of $20.3 million. However, following its change of status, NYSE showed a massive profit of $45.5 million in the fourth quarter of 2006. According to The Financial Times, the new earnings of NYSE Group Inc. serve as a progress report following its transformational year during which the exchange went public through its reverse takeover of Archipelago, in the process eliminating its long-standing cap on fees, gaining United States options market share, and making its largest round of job cuts in a decade (Gangahar, 2007). In other words, the new for-profit public NYSE is expected to continue reaping the benefits of its deal with Archipelago in the times to come. The total revenue of NYSE in the fourth quarter of 2005 was $425.5 million. In the fourth quarter, 2006, the total revenue of the exchange was $658.5 million. Financial analysts expect NYSE’s earnings to go on increasing in the coming years, seeing that the year 2007 is expected to witness the finalization of the roll out of NYSE’s hybrid market, a continual of the exchange’s integration of the electronic exchange, Archipelago, plus the completion of the Euronext deal. As a matter of fact, the Euronext deal is expected to be the next big thing to change NYSE’s life as a stock exchange. Shareholders have already approved of NYSE’s deal to merge with the pan-European exchange Euronext, creating the first transatlantic equities exchange in the process. The deal costing $14.3 billion is expected to close as early as April 2007 (Gangahar, 2007). NYSE has also announced its terms for an alliance with the Tokyo Stock Exchange in order to cooperate in a variety of business areas. Recently, the NYSE was further seen purchasing a five percent stake in the National Stock Exchange of India. Next, the exchange is eying China for a new deal to meet its goal of forming a â€Å"24-hour, truly global exchange† (Gangahar, 2007). Still, analysts are eying Euronext as the next biggest hope of NYSE to make gigantic profits. The shareholders of Euronext NV, a stock exchange incorporated in the Netherlands and based in France, have also approved the acquisition of Euronext by the New York Stock Exchange. And, in fact, NYSE has also launched its first offer for Euronext shares through the new NYSE-Euronext entity. In January 2007, The Financial Times reported that NYSE has already begun to offer 0.98 of a share in the new transatlantic exchange, for each Euronext share held before this time, in addition to $27.75 in cash. Alternatively, the first transatlantic equities exchange allows Euronext shareholders to opt for 1.2633 shares in the new company for each existing share, or to take a straight cash equivalent of $123.76 per share (Flaherty, 2007; Sliva, 2007). The completion of the Euronext’s deals with NYSE depends on the latter acquiring at least fifty percent of all Euronext shares (Sliva). Seeing that only two percent of Euronext shareholders have disapproved of the idea of the creation of the world’s first transatlantic equities exchange, in all probability the deal will go through (Gangahar, 2006). Regulators in both the United States and in Europe have signed an agreement on the question of market oversight of the new transatlantic equities exchange (Flaherty). According to a news report published in The Financial Times, the new deal truly is a â€Å"clear signal that isolationism is an untenable stance amid the rapid consolidation of global stock and derivative exchanges.† The deal has additionally been described as a â€Å"slap in the face† for those who claimed aforetime that such deals are possible only between European nations, and a transatlantic merger would result in a â€Å"regulatory creep† from the United States to Europe (Gangahar, 2006). NYSE Euronext, the next big thing on NYSE’s business agenda, is expected to have a market capitalization of $27 billion. And, the combined global market capitalization of companies that are listed on NYSE Euronext, is expected to be $25,800 billion – almost four times the combined market capitalization of companies that are listed on the London Stock Exchange (Gangahar, 2006). The next big thing about to happen to NYSE is further expected to alter the dynamic of a rapidly changing industry. In the past, the NYSE and its main rival, the Nasdaq, had been losing the battle for new listings to Hong Kong and London. Besides, smaller companies, especially from Russia and China, were seen to rush to London’s Aim market, attracted by cheaper listings and easier standards (Gangahar, 2006). NYSE Euronext is expected to change these market dynamics, if for nothing else, then for the excitement it has engendered among those who trade in equities around the world. The NYSE and Euronext have both agreed to proceed as separately regulated entities. To put it another way, even if the United States regulatory regime is found to be too harsh by European companies, NYSE Euronext would present them with the option to list on Euronext alone. In so doing, the combined group is expected to benefit (Gangahar, 2006). What is more, analysts expect all investors of NYSE and Euronext to benefit through the deal (Bruno, 2006). Only time will tell the exact value of these benefits from year to year. References 1. Bruno, Joe Bel. (2006, December 15). â€Å"Individual Investors Stand to Benefit as NYSE closes in on Euronext deal.† The Financial Times. 2. Flaherty, Anne. (2007, January 26). â€Å"SEC, European Regulators Agree On Market Oversight of NYSE Euronext.† The Financial Times. 3. Gangahar, Anuj. (2006, December 23). â€Å"NYSE and Euronext Recast an International Dynamic.† The Financial Times. 4. . (2007, February 2). â€Å"Archipelago Deal Lifts NYSE Profit Stock Exchanges.† The Financial Times. 5. Martinez, Michael J. (2006, March 8). â€Å"NY SE Goes Public After Two Centuries As Not-for-profit Exchange.† The Financial Times. 6. Sliva, Jan. (2007, January 10). â€Å"NYSE Opens Offer for Euronext Shares.† The Financial Times.

Dialectics in Oryx and Crake Essay Example for Free

Dialectics in Oryx and Crake Essay Canadian author Margaret Atwood’s novel Oryx and Crake, is about an anti-utopian society that chronicles the collapse of civilization and corrupt medical practice. The town’s morals are highly questionable, in that the majority of the citizens approve of gene splicing, transgenic animals, like mixing a dog’s genetic code with a wolf, and transplanting animal organs in human beings. The book poses a question of what is truly ethical in medical practice? This story has an immediate correlation to the island of Dr.   Moreau, by H. G. Wells, in which a mad scientist creates a dysfunctional society of genetically spliced transgenic animals as well. Like The Island of Dr. Moreau, Margaret Atwood relies on dialectical elements. Dialectic is a classical philosophy originated by the Greeks that depended on the furthering of society through thesis and antithesis. In modern day it has developed between most scholastics as a fine art of persuasion. It is ever present in Oryx and Crake through the dialectics produced through Crake’s insanity. His main dialectical argument is that society has become morally bankrupt and is due for a change and Crake claims intellectual right over all of man kind. His views are presented as deliriously radical, but there is irony in the fact that the University that Crake attends is named Asperger’s U. A term used to describe people who are usually extremely intelligent and often very eccentric, it be could argued that Atwood hints to imply Crake may be the correct one after all, and that the rest of society is wrong. This virtually tyrannical takeover of both the world and the lives of Oryx and Snowman are done entirely through aggressive persuasion. In the formation of Crake, Atwood creates an insanely ranting lunatic, with whom in the end the reader has no choice but to sympathize. The dialectic argument that is posed here is that the dye is cast. Atwood, acknowledges that our society’s morals tread a fine line from damnation, and she writes a novel that puts us one step over that line. The reader has no choice but to sympathize with Crakes’ actions because he is a product of an unbearable world, not too distant from our own. The novel itself, poses a persuasive argument to the reader, in that all of the occurrences in the plot are rationally plausible. There are scenes in the novel where the two men, Crake and Snowman, are attending college together and enjoying their favorite pastimes. These hobbies include, watching nudie news, live executions, and child pornography. In the beginning moments of the lives of the two main characters, the reader views a demoralized world, in which it appears even the plot’s hero is desensitized to the plight of his society. The ironic and reasonable argument posed is that all of these things they are doing, we can do today in our society. At the same time, child pornography, nude news, and live executions online are all either frowned upon and remotely new to our society. Atwood presents the enjoyment of these practices like they are common occurrences. The same goes for gene splicing. It is widely debated as an immoral and illegal act, but it is reasonable enough to think that with the passing of time eventually a law can be passed to legalize both gene splicing and child pornography. This would inadvertently make the use and distribution of these practice more heavily abundant in society and change the moral makeup of the people as a whole. A third persuasive argument the novel poses, and this is more from a perspective of female empowerment, is the idea of polyandry. It is historically a man’s fantasy and an empowering element for the man, while degrading to the woman, for a man to have two wives. Atwood poses the exact opposing scenario in this novel. On one end the idea of polyandry is implied through the relationships both Snowman and Crake have with Oryx. It is directly inferred to in that the Crakers only breed when they are polyandrous. This like most of the novel is a play on societal norms. Underlying in the dialectic argument of the novel are societal implications. For example, by Atwood calling Crakes’ creations the Crakers, she creates an implied connection on words to the Quakers, who are known for starting their own Christian new world. Crake also embodies the values of real time corporations, in that he creates a medical demand for his products through unleashing a virus. His behavior can only be expected by his inherent capabilities and by him being the product of a moral-less society. Atwood’s novel is also fueled by human nature, the horrific experiences the characters go through and their apathetic reactions actually seem believable because they are so human. An example of this is shown in the scene where Crake has just destroyed society as we know it and snowman watches the devastation on the internet, The whole thing seemed like a movie†¦The worst of it was that those people out there – the fear, the suffering, the wholesale death – did not really touch him (Atwood, 2004). It is ironic that Atwood makes a reference to the end of society being like a movie; this exposes snowman’s adolescent and distant nature, as well as makes him appear more human. This also connects back to the live executions witnessed online earlier in the novel. These are examples of Atwood using real time human tendencies to show her characters’ disenfranchisement from society. The actions following this scene consist of snowman leading the Crakers out into the new world in which they find glow-in-the-dark bunnies running rampant. This is another societal implication in that this was the actual result of transgenic Dr. Eduardo Kac, who spliced rabbit and jellyfish DNA in the year 2000. In sum, the dialectic philosophy is present in Margaret Atwood’s novel, Oryx and Crake in that it poses multiple arguments. It supports these arguments through real-time societal implications, believable characters, and a radical thesis carried out by Crake. Atwood’s literary genius is revealed in the fact that, all three of these elements draw sympathy from the reader, and in effect persuade the reader to believe the rationale behind the destruction of their own society.

Sunday, July 21, 2019

Media In The Game Of Cricket In India

Media In The Game Of Cricket In India This essay intends to argue that cricket in India has forged an uneasy juxtaposition of national, regional and global identities. By looking at the pre and post independence periods in India and contemporary time, the essay will show that these identities have differed or developed according to national or, regional global developments of the time. 2.0 Cricket during British India Cricket was first introduced by the British in 1721 when they were playing on a western Indian beach (Bose 1990, p.16).The early days of cricket was a platform for communal identities following the British divide and rule policy which also involved many cacophonous inducing constitutional reforms and legislations ( Stern 2003, p.19). For instance, communalism between the Indians and Muslims found expression in the Pentagular cricket tournament in 1937 that had teams pitted against each other along their religious backgrounds (Bose 1990, p.33.) These tensions persisted beyond the Partition in 1947 which resulted in the creation of Pakistan, as cricket in India acquired nationalistic overtones above and over the existing communal identities. One might expect that any colonial legacy would be strongly resisted by the colonized. On the contrary, cricket was embraced in India as a national game and this should largely be attributed to Gandhis nationalist movement which was principally focussed on non violence and love. He had urged people to accept the British for their good deeds and ignore their evils (Bose 1990, p.17). This simply meant that cricket would generally be accepted by the Indians as one of the benign effects of the imperial rule after independence. Hence, despite deepening communalism, cricket at this stage served as a consolation to many Indians who had been subjected to years of systemic oppression. 3.0 Post- independence : Economic developments and cricket The end of British occupation in India marked the beginning of cricket as a vehicle for entertainment as well as the appropriation of nationalism and consumerism. Under President Nehru, cricket became a tamasha spectacle as he was an active promoter of the game. Unlike the British, the game could not be played politely before an elite crowd in India. Instead, due to the exuberant nature of the masses, cricket in India had to be celebrated like a festival with popular Indian celebrities like Dilip Kumar attending the games (Bose 1900, p.37, 165, 218). One can attribute the festivity nature of the game to the economic development in India. Since India adopted economic socialism, a hybrid model between socialism and capitalism, masses from villages started coming to the cities to look for job opportunities (The Parliament of Commonwealth of Australia 1998, p.3). As a result, the value of entertainment took precedence over nationalistic sentiments as cricket became a source of escapism that allowed these masses to overcome the drudgery and hardships of their daily lives. Furthermore, in the absence of one day test matches during this period, crick et was played over five days and hence became a definite source of entertainment. Conversely, the appropriation of cricket primarily as an identity for entertainment has resulted in critics belonging to the higher strata of the Indian society to argue that India has failed to generate a body of cricket literature beyond journalism (Sen 2005, p.95). These critics believe that owing to the rich tradition and history of the game in India, cricket should not be confined within the spheres of entertainment but instead be used to document the progress and development of the nation. Hence, this criticism exposes the possibility of existing tensions between various classes in India regarding the general appropriation of cricket as a source of entertainment. 3.1 The intervention of media in the game of cricket in India 3.2 Assertion of Global/ National Identities It would be unjust to affirm that the value of entertainment has wholly displaced the nationalistic overtones associated with cricket in India. With membership of the state being a crucial source of national identity, the Indian media has played an integral role in fostering a strong connection between citizens and the nation through the televising of cricket matches involving the Indian national team (Mahajan 2005, p.120).The increasing commercialization of the game ignited nationalism as Indians looked towards cricket to assert their global identity. With the screening of one day test matches on television, many Indians could now bask in glory by watching their nation frequently defeat financial powerhouses and developed nations, like its former colonizer, England, at the game of cricket. Cricket therefore transformed into a barometer of a nations self worth and a tool for global and regional dominance. For instance, in 2001, the controversial dismissal of Sachin Tendulkar for chea ting in a game umpired by Mike Dennes resulted in a massive uproar in India as effigies of Dennes were burnt and the Board of Control for Cricket in India threatened to withdraw itself from the International Cricket Council. This exemplifies the interlink between cricket and global identity as Indians regard the accusations of cheating as an insult on their nation (Crick 2007, p.5). The media has also been instrumental in spreading the game to the remote villages in India. As a result, smaller towns started to produce players who made it into the national team. For instance, the rural village of Jallandher is the birth place of famous Indian cricketer, Harbajhan Singh, while Mohammed Kaif hails from Allahabad (Ugra 2005, p.88). Since the national team is made up of players belonging to various regions and religions, it may seemingly reflect the collective identity and nationalistic spirit of India. However, this collective identity seems artificial and uneasily juxtaposed between communal identities. For instance, Muslims in India are still being accused of supporting Pakistan during India- Pakistan matches (Crick 2007, p.5). Although Guttmann(2003, p.369) argues that sports can allow ethnic or religious minorities to be part of the collective identity without forgoing their individual identities, the Indian case proves to be of contrary and suggests that it is difficult to forge a singular hegemonic national identity. In addition, with Indian Diaspora scattered throughout the world due to globalization, the Indian media has been highly influential in helping these communities to cling on to their Indian identities through the televising of cricket matches (Majumdar 2008, p.129). However, this has led to the questioning of the allegiance of these immigrants to their newly adopted countries. For instance, the British Conservative Minister, Norman Tebbit once proclaimed that Indian immigrants in the United Kingdom should display their loyalty to their new home by supporting the English cricket team instead of the Indian team (BBC News 2006). This essentially puts the Indian immigrants in a predicament as they are presented with two conflicting global or national identities: India will consider them as traitors if they were to support any other country apart from India while, the countries that they live in would label them as sojourners if they elected to support India during the matches. 3.3 Consumerism and cricket in India Next, the close intertwine of cricket with consumerism has led to the creation of many alternative identities within the nation. Firstly, the liberalization of the Indian economy and the widespread effects of the media, meant that cricket had infiltrated the lives of the marginalised middle classes belonging to many of the rural areas in India (Sen 2005, p.103). This has resulted in the creation of a new consumerist society. These groups often do not know the nuances and technicalities of the game but adopt cricket as a reflection of their metropolitan life style and identity. For instance, these groups idolize cricketers as national celebrities and as a symbol of their metropolitan self. On the flip side, the appropriation of cricket merely as an identity for modernity might be resented by the puritans of the game who vehemently insist that the passion for the game can only be developed through the thorough understandings of its technicalities. Secondly, consumerism is also said to have liberated Indian womens role in cricket although, the game largely continues to have masculine connotations. Women have started to religiously follow cricket due to players like Rahul Dravid and Dhoni who are adored for their good looks. This marks a move away from the ideal notion of an Indian woman who is supposed to be traditional and domesticated. Furthermore, these women are not merely passive followers of the game. They play active roles in cricket as well. For instance, there is a female Indian national cricket team and Bollywood actresses like Priety Zinta own local cricket teams. These women signal the arrival of the new modern yet feminine Indian woman who shares like interests of the game with her husband or male acquaintances (Sen 2005, p.105). However, there is a tendency by traditionalists to equate the modern Indian woman with westernization, therefore creating a possibility of a struggle between the values of the East and the West. Despite the apparent liberalization of women through cricket, ideas of masculinity associated with the game still force themselves through. The female national team does not get the due recognition or exposure unlike its male counterpart. Furthermore, the presence of women in a game played and dominantly viewed by men means that these women would still be objectified and may be treated as sexual fantasies. This certainly exposes the tension between the masculine identity and the identity of the liberated Indian woman within the nation. Last but not least, the heavy monetizing of cricket in India also marked the beginning of match fixing and gambling scandals. During the period of 2000-2001, India was embroiled in match fixing scandals following the arrest of South African cricket captain Hansie Cronjie (Majumdar 2004, p.310). As a consequence, the national identity fostered by the game suffered a major blow as masses began to lose their romanticisation with cricket and started to doubt the performances of the national team. This illustrates that global developments can have significant impact in the shaping of a national identity. 4.0 Cricket in contemporary time 4.1 Fervent nationalism (Jingoism) During recent times, Indian nationalistic aspirations associated with cricket has transcended beyond patriotism and developed into jingoism. The nature of one day test cricket matches mean that the final outcome of the games is of the utmost importance to an Indian cricket fan. Since cricket victories have become the platform to the Indian nations assertion in the global and regional arena, there has been immense pressure on the national team to churn out victories. Whenever the team lost, Indian cricket fans would behave in an extreme and appalling manner. For example, when India lost to Australia during a World Cup match in 2003, fans burnt the effigies of the Indian players and carried out mock funeral processions of the players outside their homes. This is ironical because it was the same fans who celebrated the success of their team which defeated Pakistan in the tournament by placing players like Sachin Tendulkar and Saurav Ganguly on a pedestal and worshipping them as gods dur ing the Hindu festival of Shivarathiri (Majumdar 2004, p.346). Moreover, fans have become more vocal in expressing their dissatisfaction with the Indian national teams affairs, signalling their increasing stake in the game. For instance, following crowd favourite Gangulys exclusion from a test match, widespread protests erupted in Kolkata as fans set up road blockades and carried out mock hangings of the team coach(Express India 2005). 4.2 India- Pakistan rivalry continues in Cricket The political tensions within the South Asian region continue to exist since the Partition in 1947. Cricket therefore remains a battleground and a reflection of India- Pakistans hostile sentiments with one another. Mahajan (2005, p.117) argues that history continues to underpin the politics of friends and foes and the relationship between India and Pakistan is of no exception. The history starting from the hostility between the National Indian Congress and the Muslim League before independence, the bloodshed during the Partition and the continuing struggle over the control of Kashmir carries on to reinforce enmity between both nations (Mcleod 2008, p.1). As such, cricket cannot be played as a normal and friendly game between both teams. Furthermore, the matches do not symbolize a competition between two sporting nations. Instead, the anathema of communalism kicks in as India- Pakistan matches become a faceoff between the Hindus and Muslims. Muslims in India are also viewed suspiciously whenever these two teams clash. Hence, this supports the view that the collective national identity forged by cricket in ethnically diverse India has struggled to transcend beyond the considerations of religion. Besides, Indian politicians and the media have continued to exacerbate the relationship between the nations in the name of nationalism. For instance in 2003, following India s victory over Pakistan in a quarter final match, the ruling party at the time, Bharata Janata Party (BJP), announced that the national players need not pay income tax for their payments arising from the match (Crick 2007, p.10). The BJP thus appropriated the win to reinforce their communalistic sentiments and quest for a dominant Hindu ideology in India. The Indian media on the other hand, fuels nationalistic sentiments by dramatizing the matches between the nations. Newspapers often represent India- Pakistan matches with imagery of war (Chatterjee 2004, p.625; Dasgupta 2004, p.577). However, attempts at mending the ties between both the nations need to be acknowledged. For instance, the India Pakistan Goodwill cricket series in 2004 was a diplomatic plan to forge a stronger relationship between both nations (Hutton 2008, p.146). Whether cricket will propagate peace within the South Asian region or will be continued to use as a declaration for fervent nationalistic and communalist sentiments, ultimately lies in the hands of the politicians. 4.3 Cricket continues to represent the Indian Demographic Despite the uneasy union of various identities, it needs to be conceded that cricket continues to represent the demographic in India. To illustrate this view, the Oscar nominated Bollywood film, Laagan, will be used as an example because films play a large role in Indians lives. Laagan was based on a real life incident that occurred in 1911. A group of bare footed Indian players from Mohun Bagun had defeated an English team in a game of soccer (Ugra 2005, p.91). However, with certain modifications to the screen play, the filmmakers decided to adapt the incident using the popular Indian game of cricket instead of soccer. This shows us the extent that cricket has become a modern symbol of the Indian national identity as the movie goers were able to identify themselves with the popular sport. It is highly doubtful that the movie would have been well received by the masses if it was based on any other game apart from cricket. 5.0 Conclusion Cashman (1980, p.111) argues that a cricket crowd is the reflection of the homogeneity of a nations population. However, this must be viewed with reservations in the case of India because cricket has been a vehicle for the expression of various alternative identities. Despite dominantly representing the aspirations of a third world Asian country on the international stage, Indian cricket has also created contradicting identities within the nation itself. It is further contended that these differing identities have gone on to aggravate political tensions within the South Asian region as demonstrated by the India- Pakistan matches. It is hence concluded that India will only be able to foster a singular Indian identity through cricket if it is able to reflect each and every communitys diversity in the universal (Carens 2000, p.166-73).

Saturday, July 20, 2019

Are Bull Markets Supported By Rational Growth in Stock Valuations? :: Finance Financial Economics Essays

Introduction â€Å"The rich get richer† is a frequently heard adage in the United States, a country quickly associated with capitalism. US financial markets make headline news on a daily basis, so people are well aware when the domestic stock market’s indices rise or fall. Given the widespread distribution of information on the stock market’s performance, much excitement can easily be generated during a bull market, broadly defined as a trend during which stock prices are climbing. Does the publicity and excitement surrounding a bull market further perpetuate rising stock prices? A look at historic daily closing values for the S&P 500 index from January 2, 1997 to December 31, 1999 reveals overall growth of 99.35%[i], which on average indicates similar growth in the stock prices of the companies included in the index. Clearly, this three year period falls within a bull market, since the S&P 500 is commonly utilized to represent average performance of the stock market on the whole. A return of 99.35% on an investment is excellent and far exceeds the general return on â€Å"risk-free† investments like FDIC insured savings accounts or Treasury bills. [i] Percent change calculation derived from widely published market data Examination of Common Stock Valuation to Account for Rising Share Prices Like most economic evaluations, the decision to purchase a share of a company’s stock is based on an individual’s willingness to pay versus the current selling price of the share. Fundamentally, the willingness to pay is determined by a valuation of that share of stock. For a given share of common stock, the willingness to pay is, or should be, linked to the present value of the stream of future cash flows that the investor will receive from expected dividends and through any expected capital gain for selling the share at a higher price than at which it was purchased.[i] Thus, there are three main factors the affect the valuation of a share of common stock: future dividends, future market price of the share, and the discount rate used. [i] Fundamentals of Financial Management, Eugene F. Brigham & Joel F. Houston, Harcourt College Publishers: Forth Worth, 2001. (p. 409) Future Dividends Are Bull Markets Supported By Rational Growth in Stock Valuations? :: Finance Financial Economics Essays Introduction â€Å"The rich get richer† is a frequently heard adage in the United States, a country quickly associated with capitalism. US financial markets make headline news on a daily basis, so people are well aware when the domestic stock market’s indices rise or fall. Given the widespread distribution of information on the stock market’s performance, much excitement can easily be generated during a bull market, broadly defined as a trend during which stock prices are climbing. Does the publicity and excitement surrounding a bull market further perpetuate rising stock prices? A look at historic daily closing values for the S&P 500 index from January 2, 1997 to December 31, 1999 reveals overall growth of 99.35%[i], which on average indicates similar growth in the stock prices of the companies included in the index. Clearly, this three year period falls within a bull market, since the S&P 500 is commonly utilized to represent average performance of the stock market on the whole. A return of 99.35% on an investment is excellent and far exceeds the general return on â€Å"risk-free† investments like FDIC insured savings accounts or Treasury bills. [i] Percent change calculation derived from widely published market data Examination of Common Stock Valuation to Account for Rising Share Prices Like most economic evaluations, the decision to purchase a share of a company’s stock is based on an individual’s willingness to pay versus the current selling price of the share. Fundamentally, the willingness to pay is determined by a valuation of that share of stock. For a given share of common stock, the willingness to pay is, or should be, linked to the present value of the stream of future cash flows that the investor will receive from expected dividends and through any expected capital gain for selling the share at a higher price than at which it was purchased.[i] Thus, there are three main factors the affect the valuation of a share of common stock: future dividends, future market price of the share, and the discount rate used. [i] Fundamentals of Financial Management, Eugene F. Brigham & Joel F. Houston, Harcourt College Publishers: Forth Worth, 2001. (p. 409) Future Dividends

Friday, July 19, 2019

General George Smith Patton Essay -- Papers

General George Smith Patton A burning desire to go forth and reach personal conquests exists inside every man. This passion often navigates the would-be hero into a state of tragedy involving pain and suffering for those around. One individual, in particular, inflicted strain and duress on others with a harsh, and often criticized unorthodox style of leading when he took his campaign across Europe and into Germany. General George Smith Patton, Jr. led an expedition across a continent to rid the world of its Nazi powers. This journey marked the conquest of perhaps the world's greatest war general and his reputable demeanor. Patton experienced respect and admiration throughout his life, starting very early when he was just an infant. He was born into a highly respected and extremely wealthy family in San Gabriel, California. It was this early taste of good fortune that allowed Patton to develop a taste for fine things such as horses. Growing up he was an avid polo player and became very good especially in college. After attending exquisite private schools, Patton left and attended the U.S. Military Academy and graduated in 1909. (WB 140) After his graduation, Patton joined the cavalry and eventually served in World War I. Patton was an excellent physical specimen and a strong addition to any early fighting battalion. Along to go with his sleek build was a strong mentality of perseverance and excellence, which he drilled into his life everyday. "From his earliest years, he believed himself destined to be a soldier. Much of his life was spent in the limelight. As a young cavalry officer and well-rounded athlete, he competed in five events during the 1912 Olympic games held in Stockholm, Sweden. He placed ... ... Essame, H. Patton: A Study in Command. New York: Charles Scribner's Sons. 1974. Farago, Ladislas. The Last Days of Patton. New York: McGraw Hill Book Company. 1981. Mysak, Joe. "Patton: The Man Behind the Legend 1885-1945." National Review. 38 (April 25, 1994): 52-53. "An Educated Army." Africe News Service. 11 Feb. 2000: 179. Patton. Dir. Franklin J. Schaffner. 20th Century Fox, 1970. New Line Home Video, 1985. "Patton." Encyclopedia of World Biography. Second Edition. 12. Orozco-Radisson. Cole. Detroit. 1998. "Patton's Plan for Winning the War." Newsweek. 8 Mar. 1999: 48. "General George S. Patton, Jr. Biography." 2000 WriteForCash.com. http://www.allsands.com/generalgeorgep_ra_gn.htm. "George Smith Patton, Jr." GSP. 1 Jun. 1998. http://www.angelfire.com/sys/popup_source.shtml.

Computer Networks :: Technology, Network Resources

Computer networks like internet necessitate network resources, i.e. bandwidth, buffer spaces, etc in order to accommodate the arriving packets at router buffers [25]. When the arriving packets cannot be accommodated due to lack of network resources, this indicates occurring congestion at router buffers of networks [21]. Congestion can deteriorate a network performance [22, 25] through growing the packet loss probability due to overflow as well as the mean waiting time for packets in the queueing network. In addition, congestion may reduce the throughput and increase the packet dropping probability precedes the router buffers have overflowed. Congestion can also generate unmaintained average queue length ( ), and this may lead to build up the contents of router buffers, and thus many arriving packets may drop or lose at the router buffers. Many researchers have proposed methods with aim to control congestion at router buffers of networks [1, 2, 4, 5, 8, 14, 15, 16], i.e. AQM methods [1, 2, 4, 5, 6, 7, 8, 13, 14, 15, 16]. Each AQM is proposed as a congestion control method that identifies congestion at router buffers in an early stage, which means before the router buffers have overflowed. The most known AQM method is RED [14], Gentle RED [16], the Adaptive GRED [2], Adaptive RED [15], Random Early Marking (REM) [7], Dynamic Random Early Drop (DRED) [8] and some discrete-time queue analytical models [1, 4, 5, 6] which were constructed depending on some of AQM techniques. For example, DRED analytical models which they constructed by analysing two queue nodes [5] and three queue nodes [1] based on DRED and using discrete-time queues mechanism [26]. GRED analytical model [4] and BLUE analytical model [6] were constructed depending on GRED and BLUE, respectively and utilising discrete-time queues mechanism. As mentioned previously, RED was proposed as a congestion control method, but RED can degrade the network’s performance due to the following causes: 1) abruptly RED can increase its arrival rate aggressively, thus the RED’s router buffers may overflow. Therefore, every arriving packet will lose. 2) At a particular time, the RED’s congestion measure ( ) value may be below the value of minimum threshold position at the router buffer ( ). This indicates no packet can be dropped. However, for a short time the arrival rate increases and making the router buffer overflowing. Nonetheless, the value increases but still smaller than the value of .

Thursday, July 18, 2019

Can Technology Replace Teachers Essay

TV, computers have fully integrated into urban life in many spheres like education, entertainment, and commerce, and therefore, some people consider that the technology such as multimedia teaching would replace teachers in class. I would say this does not sound very convincing because the superiority of the teachers are obvious. The first and most apparent advantage that face-to-face conversation is a vital ability for the environment of the social working is clear. Teachers give students direction to have a good grasp to work in the team or respect each other. It is possible for one to have a video communication with teacher to achieve that, however, the meaning of much of what we say depends on our body language and tone of voice which can not be transmitted by the computers. The interaction between teachers arid students is the core of teaching process. Additionally, it is generally thought that multimedia always connects with Internet which is a double-edged sword. The Internet with innumerable news sources about curriculum let us make the paradox of choice. For instance, we downland a mass of materials for TOEFL tests but do not know which one to start. Teachers play significant roles to guide our study, and they can tell us where we begin with, what we should do, and which reference we should choose, hence their proposal always make a huge difference especially in a brand new discipline. As a facilitator ,teacher can make us learn efficiency. Whats more, students,with low self-control, also easier to indulge in bad or rather faulty information and act on it. Teachers also play significant roles in supervising students. In conclusion, the computer has been widely used in class,it cannot replace the role of teachers who impersonated an essential part of modern education. Nevertheless,multimedia teaching facilitates our education like PPT teaching which can avoid the chalk dust. Teachers can use this trait to mend and consummate our education.

Wednesday, July 17, 2019

Through the Tunnel

finished The Tunnel In this invoice, Through The Tunnel, thither are three settings that all be something different. The safe beach symbolized him fluid cosmos a fry. On the safe beach, his fuss was there to protect and be there for him. The wild beach was where Jerry wanted to go. It was pickings a step out into the valet to him. He wanted to be disengage and hold up a man. The journey with with(predicate) the dig symbolized Jerry going from a child to an adult.He challenged himself to go through the dig so he would feel get toed and ultimately be a man, something his mother would neer understand. Other than the settings, there are more different symbols in the story that sustain readers figure out the meaning of the consentaneous story. One symbol from this story would be lousiness. When Lessing writes, He struggled on in the darkness, the darkness symbolizes Jerrys lack of knowledge or the affright of the unknown.He doesnt actually know how far the tunnel g et out go or if it will become narrow. Another symbol from this story would be twinkle. While Jerry was travelming through the tunnel he saw light coming in through a crack. That symbolizes that he is really close to go a man. The big meaning of Jerry do it through the tunnel is the journey from boyhood to manhood. When Jerry number one disc everyplaces the tunnel he can swim through it exchangeable the other boys, therefore, fitting a man. Jerry practices holding his breath over and over.Even though holding his breath for a long time caused him physical pain, Jerry still tells himself that he will overcome it and accomplish his goal. During the time it took him to go through the tunnel, Lessing writes that Jerry is panicking because he thinks he might not shit it out of the tunnel. This shows that Jerry was somewhat scared to become a man. When Jerry finally comes out of the tunnel on the other side, he feels like he has become independent and mature. He finally has become the man that he wanted to be. The tunnel is a the right way symbol because it shows rebirth.

Tuesday, July 16, 2019

Cellphone Addiction

Cellphone Addiction

Like every dependence, once triggered, it can be hard to stop.There are effective solutions for treating the addiction, once you identify the symptoms. Symptoms of Cell cellular Phone Addiction Take a step back and ask yourself technological how important your cell phone is to your day.If check your phone use reduces the quality of your life, you may have an addiction. Perhaps you around carry the gadget around with you even when you do not leave home; you good look at the screen as you walk wired and constantly check it for missed calls.Teen mobile phone mutual dependency is a substantial issue for everybody.Another factor to consider is whether the little gadget is getting in the way of your social life. Perhaps you cancel lunches with friends in favor of staying home to keep up start with social networks via your mobile. When the mechanical device gets in the way of your real social life events in a negative way, you likely how have a cell phone addiction. Causes There how are many causes of the addiction.

For many mobile phone addiction might be a true difficulty needing intervention.Your many friends and family members are joining neural networks too. You often â€Å"talk† to one another on the networks as your schedules keep you too busy to meet face to face.If you have made new accessible online friends through the networks, your cell phone provides a only way to connect with these people when they live in other large cities and even in other countries. You free trade media links, such as articles and photos.Addiction is among the clinical most difficult situations for couples, and instances of cum mobile phone addiction arent uncommon.Cell phone addiction is a great contemporary phenomenon.

Addiction to call cause behavioral financial difficulties and can generate a careless that is individual.Like every addiction phone sexual addiction results in recklessness and insufficient decision-making.Past using the mobile phone to speak it goes.Suddenly addiction that is texting is logical! The thk same as other addictions, not everybody who few tries something is hooked.

Find that it is hard to unplug from work and societal networks.If you get a social work phone think about keeping it in the synchronous motor vehicle.Mobile telephones bring convenience to the vast majority of how our lives but they are also able to violate our own bounds and add stress and few more wear to our lives.No one ought to be permitted to carry their phone.

Monday, July 15, 2019

Pricing Strategies of Hyundai

1 jar against 2006 neighboring(a) passing Hyundai Launches Family de end pointine scheme and Standardises move Prices The toll of owning and serving a Hyundai has never been cheaper for kiwi fruit takeists from this week. Hyundai self-propelling wise Zealand has proclaimed a revolutionist juvenile vocalisation indemnity that provide incur true disc over outlays crossways Hyundais personate orbital cavity convertible, and in some(prenominal)(prenominal)(prenominal) courtings turn intimately cheaper. know as the Family price Strategy, the policy covers the price of sign-go-string alimony h mavinst-to- safeness Hyundai separate appraise across simulations, and is the source smell toward standardised service be.Surveys by Hyundai revealed the companion already had free-enterprise(a)ly priced sincere separate, having quasi(prenominal) prices to the after marketplace competitors and in both(prenominal)(prenominal) cases thrashing them. Hyundai sore Zealand Aftermarket motorcoach ray of light Tolley utter getting the societys unfinished separate line up across the model picture was the first part of the play a foresighteds dodging to go by self-command greet as humble as execut open for only Hyundai fomites. It would exchangeablewise procure customers exact the reassurance of true(a) Hyundai separate which father with a 12 month, 20,000km warranty.The brush offescentseparate market is a ecumenic line for the motor constancy because umteen split ar nonstandard and unsafe. To armed combat this Hyundai move companion has been subtile to get multiform in this local initiative. work about with Hyundai get lodge and its suppliers has meant that we atomic number 18 able to abide some self-coloured reductions in determine to arrive at the recent Zealand consumer, say Mr Tolley. We pass judgment customers to gather from some red-blooded split savings, in particular on the bigger fomites much(prenominal)(prenominal) as Terracan, Santa Fe and the young luster tell Mr Tolley. You go away face old(prenominal) components bid take cable care s natural elevation pads project from anything up to $253 for each one belt shoot to $85 chthonic the Family price Strategy. impartial components equal anoint filters on our gas pedal engines leave brush aside from up to $38 down to $15. 75. These savings are genuine, long term and exit trail into precise agonistical serve be for our customers. Mr Tolley give tongue to Hyundai was button to great lengths than any another(prenominal)wise vehicle maker with this bare-assed determine strategy. low-toned-spirited possession hails with Hyundai were already well-nigh a given, collect to the exceedingly lofty level of pure tone and reliability in untried Hyundai vehicles, express shaft of light Tolley. Surveys such as the esteemed JD might fomite shade sentiment rated th e Hyundai Sonata as one of the originations apex lead tried cars in 2005. The US ground original spirit list sight confirm the Hyundai Tucson as the terra firmas heightsest prime(prenominal) fiddling SUV for 2005. The results generate from polling a wide 40,000 buyers of models end-to-end the USA. With results like this support up by competitive parts pricing, radical Zealanders can be received they entrust see Hyundai as an extremely good value, high quality, low cost vehicle for many days to come. move it simply, we are reassured that over a virtuoso(a) self-command cycle, no car go forth place a unwrap virtuoso(a) cost of self-command than a Hyundai. This has already been shown to be the case with Hyundais Getz, which in 2005, won the go around modest gondola appoint in the one-year Australias silk hat Cars awards pull ahead the top well supra reasonable rank for among other things, Pricing, caterpillar tread & fixedness cost and Warranty .